Publications

Research Articles (Peer-Reviewed)

  • Y. Ma, H. Zhang and Xue-Long Sun*, Azide-Reactive Liposome for Chemoselective and Biocompatible Liposomal Surface Functionalization and Glyco-Liposomal Microarray Fabrication, 2011, Langmuir, published online ASAP.
  • J. Peng, J. Jiang, W. Wang, X. Qi, Xue-Long Sun, Q. Wu, Glycosylation and Processing of Pro-B-type Natriuretic Peptide in Cardiomyocytes, Biochem. Biophys. Res. Commun. 2011, 411, 593-598.
  • S. N. Narla, Xue-Long Sun*, Synthesis of Orientated Glyco-Macroligand Based on Site-Specific Immobilization of Chain-End Functionalized Glycopolymer, Organic and Biomolecular Chemistry 2011, 9, 845-850.
  • Y. Ma, H. Zhang and Xue-Long Sun*, Spherical Glycosurface Assembling Based on Chemoselcetive and BiocompatibleImmobilization and Further Modification of Intact Liposome, Bioconjugate Chemistry 2010, 21, 1994-1999.
  • Y.Wang, S. Chalagalla, T. Li, Xue-Long Sun, W. Zhao, P. Wang, X. Zeng, Label Free Carbohydrate Biosensors Based on Polyvalent Interaction for Sensitivity Amplification, Biosensors and Bioelectronics 2010, 26, 996-1001.
  • H. Zhang, Y. Ma, Xue-Long Sun*, Recent Carbohydrate Recognition Based Targeted Drug and Gene Delivery.Medicinal Research Review, 2010, 30, 270-289.
  • S. Chalagalla, Y. Wang, D. Ray, X. Zeng and Xue-Long Sun*, Synthesis and Characterization of Oriented Glyco-Capturing Macroligand, ChemBioChem 2010, 11, 2018-2025.
  • S. Chalagalla, Xue-Long Sun*, Synthesis and Characterization of Biotin Chain-End Functionalized Boropolymer as Functional Glyco-Affinity Macroligand, Reactive and Functional Polymers 2010, 70, 471-476.
  • H. Zhang, Y. Ma, Xue-Long Sun*, Chemical Selective Surface Glyco-Functionalization of Liposome through Staudinger Ligation. Chemical Communications, 2009, 3032-3034.
  • Xue-Long Sun*,  L. Yang, and E. L. Chaikof, Chemical Selective Immobilization of Biomolecules through Aqueous Diels-Alder and PEG Chemistry, Tetrahedron Letter, 2008, 49, 2510-2513.
  • Xue-Long Sun, Functional Glyco-Affinity Precipitation for Enhanced Glyco-Proteomics. Current Proteomics, 2008, 5, 202-210.
  • Xue-Long Sun, Recent Multivalent Sialyloligosaccharide and Sialylmimetics-Based Antiinfluenza Strategies. Current Medicinal Chemistry 2007, 14, 2304-2313.
  • C. Stabler, Xue-Long Sun, W. Cui, J. Wilson, C. Haller, and E. L. Chaikof, Surface Re-Engineering of Pancreatic Islets, Bioconjugate Chemistry 2007, 18, 1713-1715.
  • J. T. Wilson, W. Cui, Xue-Long Sun, C. T. Tucker-Burden, C. J. Weber, E. L.  Chaikof, In vivo biocompatibility and stability of a substrate-supported polymerizable membrane-mimetic film.  Biomaterials 2007, 28, 609-617.
  • S. W. Jordan, K. M. Faucher, J. Caves, R. A. Apkarian, S. M. Rele, Xue-Long Sun, S. R. Hanson E. L. Chaikof, Fabrication of a self-assembled membrane-mimetic thin film on a PTFE vascular graft surface.  Biomaterials 2006, 27, 3473-3481.
  • P. Tseng, S. W. Jordan, Xue-Long Sun, E. L.Chaikof, Catalytic efficiency of a thrombomodulin-functionalized membrane-mimetic film in a flow model. Biomaterials 2006, 27, 2768-2775.
  • P. Tseng, S. M. Rele, Xue-Long Sun, E. L. Chaikof, Fabrication and characterization of heparin functionalized membrane-mimetic assemblies. Biomaterials 2006, 27, 2627-2636.
  • P. Tseng, S. M. Rele, Xue-Long Sun, E. L. Chaikof, Membrane-mimetic films containing thrombomodulin and heparin inhibit tissue factor induced thrombin generation in a flow model. Biomaterials 2006, 27, 2637-2650.
  • E. L. Chaikof, P. Tseng, S.M. Rele, S.W. Jordan and Xue-Long Sun, Surface bound thrombomodulin and heparin inhibit tissue factor-induced thrombin generation in a flow model. J. Surg. Res.  2006, 130, 203-204.
  • Xue-Long Sun*, C. Stabler, C. Cazalis, E. L. Chaikof, Carbohydrates and Protein Immobilization onto Solid Surface by Sequential Diels-Alder and Azide-Alkyne Cycloaddition, Bioconjugate Chem.  2006, 17, 52-57.
  • Xue-Long Sun*, N. Biswas, T. Kai, K. Z. Dai, R. A. Dluhy, and Elliot L. Chaikof, Synthesis and Self-Assemblies of Asymmetric Lipid Bolaamphiphile, Langmuir  2006, 22, 1201-1208.
  • Xue-Long Sun*, C. Haller, X. Wu, and Elliot L. Chaikof, One-Pot Glyco-Affinity Precipitation Purification: The Flexible Alignment of Solution-Phase Capture/Release and Solid-Phase Separation. J. Proteome Res. 2005, 4, 2355-2359.
  • T. Kai, Xue-Long Sun*, K. M. Faucher, and Elliot L. Chaikof, Design and Synthesis of Asymmetric Acyclic Phospholipid Bolaamphiphiles, J. Org. Chem. 2005, 70, 2606-2615.
  • M. Murphy, K. M. Faucher, Xue-Long Sun, E. L. Chaikof and R. A. Dluhy, Analysis of photoinitiated polymerization in a membrane mimetic film using infrared spectroscopy and near-IR Raman microscopy. Colloids and Surface B: Biointerface 2005, 46, 226-232.
  • R. Guan, Xue-Long Sun, D. Grande, S. Baskaran, and E. L. Chaikof, A Glycopolymer Chaperone for Fibroblast Growth Factor-2, Bioconjugate Chem.2004, 15, 145-151.
  • C.-M. Dong, Xue-Long Sun, K. M. Faucher, R. P. Apkarian, and Elliot L. Chaikof, Design, Synthesis and Characterization of Glycopolymer-Polypeptide Triblock Copolymers, Biomacromolecules, 2004, 5, 224-231.
  • Xue-Long Sun*, W. Cui, T. Kai, and E. L. Chaikof, A Facile Synthesis of Bifunctional Phospholipids for Biomimetic Membrane Engineering, Tetrahedron 2004, 60,11765-11770.
  • Xue-Long Sun*, W. Cui, C. Haller, and E. L. Chaikof, Site-Specific Multivalent Carbohydrate-Labeled Quantum Dots and Magnetic Beads, ChemBioChem 2004, 5, 1593-1596.
  • S. Hou, Xue-Long Sun*, C.-H. Dong, and E. L. Chaikof, Facile Synthesis of Chain-End Functionalized Glycopolymers for Site-Specific Bioconjugation, Bioconjugate Chem. 2004, 15, 954-959.
  • K. Faucher, Xue-Long Sun, and E. L. Chaikof, Fabrication and Characterization of Glycocalyx-Mimetic Surface, Langmuir 2003, 19. 1664-1670.
  • H. Hinou, Xue-Long Sun, and Y. Ito, Systematic Synthesis and Inhibitory Activity of Bisubstrate-Type Inhibitors of Sialyltransferases, J. Org. Chem. 2003, 68, 5602-5613.
  • Xue-Long Sun,* K. M. Faucher, M. Houston, D. Grande, and E. L. Chaikof, Design and Synthesis of Biotin-Terminated Glycopolymer for Surface Glycoengineering, J. Am. Chem. Soc. 2002, 124, 7258-7259.
  • Xue-Long Sun, D. Grande, S. Baskaran, and E. L. Chaikof, Glycosaminoglycan-Mimetic Biomaterials 4: Synthesis of Sulfated Lactose-Based Glycopolymers that Exhibit Anticoagulant Activity, Biomacromolecules 2002, 3, 1065-1070.
  • J. Feng, P. Y. Tseng, K. M. Faucher, J. M. Orban, Xue-Long Sun, and E. L. Chaikof, Functional Reconstitution of Thromobomodulin with a Substrated Membrane-Mimetic Polymer Film, Langmuir 2002, 18, 9907-9913.
  • S. Baskaran, D. Grande, Xue-Long Sun, A, Yayon, and E. L. Chaikof, Glycosaminoglycan-Mimetic Biomaterials 3: Glycopolymers Prepared from Alkene-Derivatized Mono- and Disaccharide-Based Glycomonomers, Bioconjugate Chem. 2002, 13, 1309-1313.
  • H. Liu, K. M. Faucher, Xue-Long Sun, J. Feng, J. M. Orban, and E. L. Chaikof, A Supported Lipid Bilayer as a Membrane-Mimetic Cell Encapsulation Barrier, Langmuir 2002, 18,1332-1339.
  • Xue-Long Sun, H. Liu, J. M. Orban, L. Sun, and E. L. Chaikof, Synthesis and Terminal Functionalization of Polymerizable Phosphatidyl ethanolamine, Bioconjugate Chem. 2001, 12, 673-677.
  • H. Hinou, Xue-Long Sun, and Y. Ito, Bisubstrate-Type Inhibitors of Sialyltransferase, Tetrahedron. Lett. 2002, 43. 9147-9150.
  • C.-T. Guo, Xue-Long Sun, O. Kanie, K. F. Shotridge, T. Suzuki, D. Miyamoto, K. I.-P. Hidari, C.-H. Wong, and Y. Suzuki, A Discovery of An O-Glycoside of Sialic Acid Derivative That Inhibits both Hemagglutinin and Sialidase of Human Influenza Virus, Glycobiology 2002, 12, 183-190.
  • Xue-Long Sun, Y. Kanie, C.-T. Guo, O. Kanie, Y. Suzuki, and C.-H. Wong, Syntheses of C-3 Modified  Sialylglycosides as Inhibitors of Influenza Hemagglutinin and Neuraminidase, Eur. J. Org. Chem. 2000, 14, 2643-2653.
  • Xue-Long Sun, N. Sato, T. Kai, and K. Furuhata, Novel Practical Synthesis of 2,6-Anhydro-3- eoxy-D-glycero-D-galacto-non-2-enoic Acids (KDN2en) and Its C-4 Nitrogen-modifying Derivatives. Carbohydr. Res. 2000, 323, 1-6.
  • Xue-Long Sun, T. Kai, H. Takayanagi, and K. Furuhata, A Straightforward Synthesis of a-Furyl Amide via Lewis Acid-mediated Allylic Substitution. SYNLETT 1999, (9), 1399-1341.
  • Xue-Long Sun, T. Kai, N. Sato, H. Takayanagi, and K. Furuhata, Synthesis of 4-Oxo- and 4-Hydroxyimino-KDN2en Derivatives. J. Carbohydr. Chem. 1999, 18, 1131-1138.
  • Xue-Long Sun, T. Kai, H. Takayanagi, and K. Furuhata, Synthesis of Sialic Acid Analogs with the Acylamino Groups at C-4 (N-Acyl Regioisomers of Sialic Acids). Carbohydr. Res. 1997, 298, 181-189.
  • Xue-Long Sun, T. Kai, M. Tanaka, H. Takayanagi, and K. Furuhata, Synthesis of 2,6-Anhydro-3-deoxy-D-glycero-D-galacto-non-2-enoic Acids (KDN2en) and its Hydrogenation Products. J. Carbohydr. Chem. 1997, 16, 541-547.
  • T. Kai, Xue-Long Sun, H. Takayanagi, and K. Furuhata, Oxidation Products of C-4 and C-7 Hydroxyls into the Methyl a-Glycoside Derivatives of KDN. J. Carbohydr. Chem. 1997, 16, 533-540.
  • T. Kai, Xue-Long Sun, Takayanagi, and K. Furuhata, Synthesis of Sialic Acid Analogs with the Oxime Groups at C-4 or C-5 of KDN. J. Carbohydr. Chem. 1997, 16, 521-532.
  • Xue-Long Sun, T. Kai, M. Takayanagi, and K. Furuhata, A Novel Glycosylation of 3-Deoxy-D-glycero-D-galacto-2-nonulosonic Acids. Chem. Pharm. Bull. 1996, 45, 795-798.
  • Xue-Long Sun, H. Takayanagi, K. Matsuzaki, H. Tanaka, K.Furuhata, and S. Omura, Synthesis and Inhibitory Activities of Isochromophilone Analogues against gp120-CD4 binding. J. Antibiotics, 1996, 49, 689-692.
  • T. Kai, Xue-Long Sun, M. Tanaka, H. Takayanagi, and K. Furuhata, Reaction products from Fisher's Methylation of 3-Deoxy-D-glycero-D-galacto-2-nonulosonic Acid (KDN). Chem. Pharm. Bull. 1996, 44, 208-211.
  • M. Tanaka, T. Kai, Xue-Long Sun, H. Takayanagi, and K. Furuhata, Synthesis of N-Glycosyl-8-O-Sulfoneuraminic Acid. Chem. Pharm. Bull. 1995, 43, 2095-2098.
  • M. Tanaka, T. Kai, Xue-Long Sun, H. Takayanagi, and K. Furuhata, Synthesis of Fluorescent 4-Methyl-7-Thiocoumaryl S-Glycosides of Sialic Acid. Chem. Pharm. Bull. 1995, 43, 1844-1848.
  • Xue-Long Sun, T, Kai, M. Tanaka, H. Takayanagi, K. and Furuhata, A Facile Synthesis of 4-Acylamino-2,6-anhydro-2,3,4-trideoxy-D-glycero-D-galacto-non-2-enoic Acids. Chem. Pharm. Bull. 1995, 43, 1654-1658.
  • S-S, Li, Xue-Long Sun, H. Ogura, Y. Konda, T. Sasaki, Y. Toda, H. Takayanagi, and Y. Harigaya, Photocycloaddition of Benzoylated 2'-Deoxyribo-nucleoside to 2,3-Dimethyl-2-butene. Chem. Pharm. Bull. 1995, 43, 144-146.
  • Xue-Long Sun, N. Haga, H. Ogura, and H. Takayanagi, Synthesis of a-N-Glycoside of 3-Deoxy-D-glycero-D-galacto-2-nonulosonic Acid (KDN) using Nucleobase and Their Photocycloaddition to 2,3-Dimethyl-2-butene. Chem. Pharm. Bull. 1994, 42, 2352-2356.
  • Y. Konda, T. Sasaki, Xue-Long Sun, X. Li, M. Onda, H. Takayanagi, and Y. Harigaya, Conformational Analysis of C3'-C8 Connected Biflavones. J. Heterocyclic Chem. 1995, 32, 1531-1535.
  • Y. Konda, T. Sasaki, Xue-Long Sun, X. Li, M. Onda, H. Takayanagi, and Y. Harigaya, Absolute Structure of 2'-Desacetoxyaustrospicatine Established by X-Ray Analysis and Circular Dichroism Spectroscopy. Chem. Pharm. Bull. 1994, 42, 2621-2624.
  • Xue-Long Sun, L. -J. Wu, X. Li, Y. Konda, and M. Onda, Chemical Studies of Tuxus cuspidata Sieb et Zucc. Chin. J. Med. Chem.,1992, 2, 31-34.
  • Xue-Long Sun and X. Li, Recent Chemical Studies on Pine Leaf Components. J. ShenYang. Pharm. Univ,1991, 8, 145-149.
  • Y. Harigaya, Y. Konda, M. Iguchi, M. Onda, X. Li, L. J. Wu, S. S. Li, and Xue-Long Sun, Spectroscopic Studies of Brusatol J. Nat. Prod. 1989, 52, 740-748.

Invited Book Chapters

  • J. Weingart, Xue-Long Sun*, “Glyco-Functionalized Quantum Dots: Synthesis and Biomedical Applications” in ACS Symposium Series Book. Ed. Xuefei Huang and Joseph Barch (ACS Books), 2011, accepted.
  • H. Zhang, Y. Ma, Xue-Long Sun*, “Chemical Selective and Biocompatible Liposome Surface Functionalization Approach” in Methods in Molecular Biology Book Series: Bioconjugation Protocols, 2nd Ed. Sonny S. Mark Editor (Humana Press/Springer Science), 2011, Chapter 16, Page 268-280.
  • Xue-Long Sun, Keith M. Faucher and Elliot L. Chaikof, “Cytomimetic Biomaterials: Fabrication, Characterization and Applications” in “Biomimetic materials and Design: Interactive Biointerfacial Strategies, Tissue Engineering, and Target Drug Delivery”. Chapter 5, pp139-157, Dillow, A. K. and Lowman, A. Eds. Marcel-Dekker, Inc. Publisher. August 2002.

Invited Commentary for New Book and Article

  • Xue-Long Sun, ChemMedChem (European Journal of Medicinal Chemistry, Wiley Interscience), 2005, 1, 159. Book Review: “Biopolymers for Medical and Pharmaceutical Applications”. Ed. Alexander Steinbüchel and Robert H. Marchessault, 1145pp, ISBN 3527311548, Wiely-VCH, 2005.
  • Xue-Long Sun, Pharmacia (Journal of the Pharmaceutical Society of Japan), 1999, 35, 1165-1166. Article Review: K. Oshima, Y. Aoyama, Regiospecific Glycosidation of Unprotected Sugars via Arylboronic Activation. J. Am. Chem. Soc. 1999, 121, 2315-2316.

Invited Preface for Journal Special Issue

  • Xue-Long Sun, Special Issue of Carbohydrate Recognition and Applications for Medicinal Research Reviews (Wiley InterScience), 2010, Volume 30 Issue 2.

Conference Proceedings

    • Xue-Long Sun, Inverse Thermal-Responsive Glyco-Polypeptide Polymer for One-Pot Glyco-Affinity Proteomics, J. Fudan University (Natural Scince) 2005, 44, 840-841. (IUPC International Symposium on Novel Materials and Synthesis & 15th International Symposium on Fine Chemistry and Functional Polymer. ShangHai, China, 10/17/-10/20/2005)
    • Xue-Long Sun and E. L. Chaikof, Capture and Release of Proteins by Stimuli-Response Glyco-Polypeptide, Glycobiology 2004, 14, 1203. [The Joint Meeting of the Society for Glycobiology and the Japanese Society for Carbohydrate Research, 2004, Honolulu].
    • Xue-Long Sun and E. L. Chaikof, Synthesis of Site-Specific Functionalized Multivalent Carbohydrate and Its Glyco-Biocapture and Glyco-Affinity Staining Applications, PMSE. Prepr. 2004, 91, 793. [2004 ACS Fall National Meeting, Philadelphia].
    • Xue-Long Sun, H. Liu, K. M. Faucher, J. Feng and E. L. Chaikof, Fabrication and Characterization of a Polymeric Lipid Membrane on a Polyelectrolyte Thin Film, Polym. Prepr. 2001, 42, 109-110.[2001 ACS Fall National Meeting, Chicago].
    • Xue-Long Sun, O. Kanie, and C.-H, Wong, Design and Synthesis of Sialylphospholipid as Inhibitors of Influenza Virus, Glycoconjugate J., 1999, 16, S165. [XV International Symposium on Glycoconjugates 1999, Tokyo].

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