{"id":16,"date":"2022-05-17T01:57:36","date_gmt":"2022-05-17T01:57:36","guid":{"rendered":"https:\/\/academic.csuohio.edu\/uz-lab\/?page_id=16"},"modified":"2023-05-12T00:28:01","modified_gmt":"2023-05-12T00:28:01","slug":"home-page","status":"publish","type":"page","link":"https:\/\/academic.csuohio.edu\/uz-lab\/","title":{"rendered":"UZ-Lab at Cleveland State University"},"content":{"rendered":"

UZ-Lab at Cleveland State University<\/h1>\n\n\n
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About UZ-Lab @ CSU<\/h2>\n\n\n

UZ-Lab@CSU aims to address the challenges in life sciences and medicine by using engineering-centered approaches. Our multidisciplinary work in collaboration with academic and industrial partners focuses on biomaterials, flexible\/piezo-electronics, tissue engineering, regenerative medicine, drug\/gene delivery and membrane separation applications. With our research efforts, UZ-Lab@CSU is ultimately aiming to develop simple, inexpensive, easy-to-use, yet broadly applicable and commercially viable platforms\/interfaces that will facilitate technological translation to clinic and have societal impact. At Cleveland State University we are based in the Chemical and Biomedical Engineering Department which is located on the fourth floor of the newly built Washkewicz Hall. Our Applied Biomedical Engineering Program operates in collaboration with the Department of Biomedical Engineering in the Lerner Research Institute of the world-renowned Cleveland Clinic.<\/p>\n\n\n\n

Research<\/h2><\/div><\/div>\n\n\n\n

The main goal of our research program is to elucidate the mechanisms underlying material structure-property relationships, material-cell and cell-cell interactions to mimic tissue architectures, control cellular behavior and enable therapeutic treatments. We particularly concentrate on 1) the development of functional biomaterials-based biodegradable and implantable flexible\/piezo electronic biointerfaces or conductive platforms for stem cell-based therapies targeting tissue regeneration with an emphasis on central\/peripheral nervous system problems; 2) the design of flexible electronics and nanoscale platforms-based drug\/gene delivery systems for on demand therapeutic treatments with a particular focus on different cancer types and ocular conditions; and 3) the fabrication of stimuli responsive polymeric membranes for bioseparations, particularly nano sized small molecules produced by the cells (i.e., extracellular vesicles). To achieve these goals, our research leverages the elements of materials science, membrane science, biology and nanotechnology, which are accompanied by the utilization of diverse tools from material synthesis and characterization, surface chemistry, stem cell biology, micro\/nano fabrication, additive manufacturing and microfluidics.<\/p>\n\n\n

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For details about our current research projects visit our group website<\/strong>.<\/p>\n\n\n

Selected Publications<\/h2>\n\n\n